Positron Emission Tomography (PET) Study With [18F]AZD4694 and [11C]AZD2184, Candidate PET Ligands for Aβ Amyloid
Status:
Completed
Trial end date:
2009-10-01
Target enrollment:
Participant gender:
Summary
The study is carried out in order to investigate if [18F]AZD4694, compared to [11C]AZD2184,
is a suitable PET ligand for in vivo imaging of Aβ amyloid depositions in the human brain. In
the study the two PET ligands will be examined in both healthy volunteers and patients with
Alzheimer's Disease. A whole body dosimetry scanning will be performed in 6 healthy
volunteers to obtain human data to estimate a safe dose.